A 0651 recording of obstetric INTENSIVE CARE Watson1 D., D. Guerin2, p Natarajan1 1ICM, 2Anaesthesia, Homerton University Hospital, London, UK Introduction. Complications of pregnancy may require admission  <a href=”http://www.selleckbio.com/belinostat-S1085.html”>PXD101 HDAC inhibitor</a> to intensive care. Homerton University Tsklinik is located within a private downtown. We have details of 144 women gave to the ICU from 1993 to 1989 (0.75% of deliveries recorded. METHODS. We conducted a retrospective case-note of obstetric patients admitted to the unit intensive care unit from January 1994 to December 2005. Results . There were 47 952 deliveries w during the period of 12 years of the study. It 175 admissions were in the obstetric intensive care unit. (0.36% of deliveries. Seventy percent of admissions were the result of surgical delivery.<br> Unlike our previous case study found there was an increased hter proportion of admissions due to bleeding and erm temperate entry with Pr eclampsia associated, or hypertension in pregnancy. There was an admission to intensive care after pulmonary embolism. There is a maternal mortality rate was in this  <a href=”http://www.selleckbio.com/pha-739358-danusertib-S1107.html”>PHA-739358 827318-97-8</a> period of 12 years compared to three Todesf cases of mothers in our previous report. This maternal mortality was associated with life-threatening coagulopathy. FINAL. The three-yearly National Confidential Inquiries into Maternal and Child Health (Cernach identify thrombosis and thromboembolism, Pr eclampsia and eclampsia, amniotic fluid embolism or bleeding, lle most causes h INDICATIVE direct obstetric Todesf in Gro Britain. you repr not sentieren the h ufigsten causes for admission to our obstetric intensive care unit.<br> REFERENCE (S. Wheatley E, Farkas A, D Watson (1996 admissions obstetrics to intensive care unit International Journal of Obstetrics at Anesthesiology 5:221 224 Confidential Enquiry on Maternal and Child Health (2007 Saving Mothers lives: .. Reviewing maternal deaths to motherhood make s more Re in 2003 Cernach 2005 2007 Available online at the 21st annual conference ESICM cemach.uk Lisbon, Portugal September 24, 2008 21 0652 S167 .. The fresh frozen plasma transfusion in critically ill patients with EN R. Gibbs1, KIL Meikle2 1Intensive Therapy Unit, 2Anaesthetics, Treliske H Pital, Truro, UK Introduction. The use of fresh frozen plasma (FFP is rising. More than 4 million units in Gro Britain and the United States each year transfused.<br> comprehensive Despite the guidelines, up to the H all transfusions half in the critically ill m for may have unsuitable (first FFP transfusion in Critcal care with a significant morbidity t, including normal increased htem risk of infection (2 transfusions and respiratory syndrome is associated Acute (3 clotting tests. classics, including normal international normalized ratio (INR be h frequently lead to FFP transfusion, but changes m owned St (INR \ 9.1 is not a pr precise prognosis of the bleeding. also has the FFP asked for prophylaxis against invasive procedures in critically ill patients in question (was 4th METHODS. This was a retrospective audit of all FFP transfusions administered to patients in a UK District General Care Intensive H Pital over a period of one year. indications for transfusion and the volume of FFP were administered in each transfusion documented.<br> to the amounts of preformed transfusion transfusion INR measurement was recorded. RESULTS. About 10% of all admissions ICU has again u FFP transfusion. total of 337 units were administered in 104 separate transfusions. indications were varied, including normal correction Gerinnungsst tion in patients with active bleeding, prophylaxis for invasive procedures (including PDA and zentralven sen catheters and correcting Gerinnungsst changes in patients without overt bleeding. was 39% in the transfusion of pre transfusion INR below 1.9. at least 23 % transfusions were under treatment with two units (400 ml or less. CONCLUSION is. A significant proportion of FFP administration is not appropriate. administration to patients admit to easy Gardens coagulation tests is widespread.<br> transfusion is not expected in this Patients in the absence of active bleeding point. In addition, a big number of e-FFP transfusion guidelines used in therapeutic doses, significant amounts of 12 15 ml / kg (4 It is important sorgf to consider valid, the information on management, that FFP transfusion is associated with significant side effects. training is necessary. REFERENCE (S. 1, Lauzier F, Cook D, Griffith L, Upton J, Crowther M. fresh frozen plasma transfusion in patients with severe patients. Crit Care Med 2007, 35:1655 1659th second Sarani B, Dunkman WJ, Dean L, S Sonnad, Rohrbach JI, Gracias VH. transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased HTES risk of infection. Crit Care Med 2008, 36:1114 1118th third Gajic O, Rana R, Mendez JL, et al. acute Lungensch ending after blood transfusion in mechanically ventilated patients. transfusion., 2004 44:1468 1474th fourth Stanworth SJ. With Evidence Based