The root meristem study showed that MI and AMI get decreased in cycle industry effluent treated sets except

at 25% concentration where the MI and AMI get enhanced. The mitotic anomalies increased with increasing effluent concentration. Similar observations were also made by various workers (Kaushik et al, 199711 and Bera Antidiabetic Compound Library and Saha, 1997).12 This ultimately causes anomalies in the cells. Results were matched with Sahu, et al, 198713 and Thangapandian, et al, 1995.14 These changes might be due to the presence of heavy metals in effluent. We are accordingly inclined to conclude that the plants growing at non-polluted areas are more suitable for medicinal purposes, since all the parameters studied have revealed declining values in plants collected from polluted area. All

authors have none to declare. “
“Infectious diseases are one of the significant causes of mortality and morbidity in developing countries. The prevalence of MRSA (methicillin resistant Staphylococcus aureus) in nosocomial infections has been on the continuous rise and its prevalence has increased from 14.3% in 1987 to 60% in 2006. 1 Recently, carbapenem resistant Gram negative bacterial superbugs have been reported from patients admitted in hospitals of India and Pakistan creating a major global health problem. 2 Resistance to available therapeutic agents and the limited development of new agents are threatening to Adenylyl cyclase worsen the burden of infections and cancers that are already the leading cause of morbidity and mortality. 3 To overcome the problem, knowledge about production of allelochemicals by the BMN 673 nmr plants has created interest in use of plants. Higher plants, as sources of medicinal compounds, have continued to play an important role in the maintenance of human health since antiquity, especially in developing countries. Historically different herbal preparations have been used for the treatment of various types of illness in Indian medicine (Ayurvedic) system.4 Although, this approach accepts the emergency use of modern drugs, but recommends the use of traditional herbal

combinations and extracts to improve health, as well as to prevent microbial infections.5 Presently, 50% of all modern drugs are also of plant origin.6 Therefore, the present investigation has been carried out to evaluate the specific antibacterial potential of three Indian plants against drug resistant clinical pathogens. The plants were randomly selected from Ayurvedic system of medicine and are already known for reducing microbial infections. The leaves of plants, Tinospora cardifolia (Thunb.) Miers, Arum maculatum L. and Andrographis paniculata (Burm. f.) Wall ex Nees were collected from Pharmaceutical Garden, IMS, BHU, Varanasi, India, and submitted in the herbarium of Botanical Survey of India (BSI) under the voucher specimen no. 417577, 11177 and 414228, respectively.