Background: SWN is a feature of tubulo-interstitial pathology and in my experience is more common than glomerulonephritis. Without awareness of the clinical features, its presence may go undetected,

as there may be no evidence (abnormal eGFR or urine dipstick) of chronic kidney disease (CKD). Methods: Review clinical records of 50 patients identified as SWN, whose symptoms were described at ANZSN 2013, to identify eGFR (MDRD), dipstick urinalysis and 24 hour protein excretion. Collate scanning reports, blood pressure measurement and treatments, along with other relevant signs. Results: 6 men and 44 women, mean age 46.8 years (range 25–92). 68% of patients with appropriate data would not have been classified with CKD according to eGFR criteria. 1 had CKD 1, 20% had CKD 2, 9% had CKD 3. Haematuria was noted in 23%, proteinuria >0.15 g/24 h find more was present in 2 patients, glycosuria in 3 patients and urine pH of selleck chemicals 7 or over in 62%. Anti-hypertensives were required in 16%. The mean blood pressure of the untreated group was 118/74. In 22 patients eGFR improved by a median of 7 mL/min/1.73 m2 (range 1–37), over a median follow up of 15 months (range 1–107). In 9 patients, eGFR deteriorated by a median of 10 mL/min/1.73 m2 (range 2–35), over

a median follow up period of 14 months (range 3–89). Urinary tract infections were documented in 60%. Small or scarred kidneys were seen in 29%. Conclusions: SWN is a significant public health threat, which with recognition and correction, may offer insights into common clinical problems. 212 THE INITIAL SIX MONTHS OF AN AUSTRALIAN RENAL GENETICS CLINIC SERVICE A MALLETT1,2, C PATEL3, J MCGAUGHRAN3, H HEALY1,2 1Department DNA ligase of Renal Medicine, Royal Brisbane and Women’s Hospital, Queensland; 2CKD.QLD and School of Medicine, University of Queensland, Queensland; 3Genetics Health Queensland, Royal Brisbane and Women’s Hospital, Queensland, Australia Aim: To describe the initial experience of a new Australian Conjoint Renal Genetics (CRG) and Inheritable Kidney Disease (IKD) Clinic program. Background: Rapid expansion

in the understanding of genetic forms of kidney disease provides opportunities to consider clinical service redesign. This is required to enable optimal translation of this knowledge into a paradigm of personalised healthcare. Methods: A clinical audit has been undertaken of the first six months (1.7.13 to 31.12.13) of the CRG-IKD Clinic program at RBWH, Queensland. Results: 71 patients from 64 families were encountered in 101 clinic appointments (96% attendance) across 23 clinic dates. Referral was most commonly from a General Practitioner (44.9%) or Nephrologist (39.1%). A renal diagnosis had been made at time of referral in 76.9% of cases. Patients were most commonly female (59.2%), with a mean age of 44years and an early stage of kidney disease (CKD Stage 1: 35.7%, CKD Stage 2: 28.6%). 12.5% and 5.