Therefore, this study used the new method to estimate the independence assumption. The present study did not identify genes Selleckchem 17-AAG involved in breast cancer; therefore, similar to previous studies,4,11,12 the family history of breast cancer, as an alternative for genetic mutations, was used. Our approach is similar to other studies using the familial history as alternatives for genetic factors to study the interactions of genetic factors in pulmonary,14 and colon,13 cancers. Conclusion Matched case-control

studies require Inhibitors,research,lifescience,medical a sample higher than 300 subjects, which was used in the present study, to examine a logical interaction. Considering the smaller standard error and –2log likelihood ratio of the case-only design than those of case-control design, we might be able to suggest that the case-only design is a better method to examine the interactions Inhibitors,research,lifescience,medical between the genetic and environmental variable involved in breast cancer. Acknowledgment This study was supported by a grant from Vice–chancellor Inhibitors,research,lifescience,medical for Research, Shiraz University of Medical Sciences. This publication constitutes a part of Rahmatollah Moradzadeh’s MSc thesis (grant

no 87-3992). The authors thank Mr Haidar Nadrian for his kind cooperation in translating the paper to English. Conflict of Interest: None declared
Rehabilitation of a critical care patient requiring prolonged ventilator support is always a challenging task for a multidisciplinary team in an intensive

care unit (ICU).1 Even after the patient is medically stable, the clinicians and therapists need to manage a multitude of medical problems by rehabilitating the patients with prolonged ventilator support. Inhibitors,research,lifescience,medical These problems include reduced oxygen uptake, impaired gaseous exchange, severe acquired neuromusculoskeletal Inhibitors,research,lifescience,medical weakness, pneumonia, postural hypotension, joint contractures, bedsores and severe depression.2 Early rehabilitation in ICU is recommended as an effective management strategy to reduce these complications that coexist with prolonged ventilation of patients in ICU.3 The practice of progressively tilting the patient using a tilt table in ICU has always been a debatable DNA ligase procedure among physiotherapists.4 Due to the lack of published studies therapeutic benefits for the tilt table procedure among patients in ICU are ill-defined.4 However, recent evidence supports the tilt table procedure as one of the main treatment technique for patients who are on prolonged ventilation.5 As the awareness of this practice is slowly picking up among the practitioners, the present report introduces a patient with tracheostomy tube subjected to progressive tilting using a tilt table, and gradual weaning from the ventilator support. Case Description A 78-year-old men, admitted to a hospital following Motorcar Accident on 3rd September 2009.